Despite having higher than average bone density, patients with type 2 diabetes paradoxically have increased risk of fracture relative to individuals without diabetes. NIH/NIAMS has awarded Prof. Donnelly a career development grant to investigate the changes in collagen properties that occur in bone tissue with type 2 diabetes and their relationship to fracture risk. Key collaborators include Prof. Deepak Vashishth at Rensselaer Polytechnic Institute and Dr. Joseph Lane at the Hospital for Special Surgery.