Lab sledding day in Cornell Plantations
Lloyd AA, Wang ZX, Donnelly E. Multiscale Contribution of Bone Tissue Material Property Heterogeneity to Trabecular Bone Mechanical Behavior. J Biomech Eng. 2015.
Abstract
Heterogeneity of material properties is an important potential contributor to bone fracture resistance because of its putative contribution to toughness, but establishing the contribution of heterogeneity to fracture risk is still in an incipient stage. Experimental studies have demonstrated changes in distributions of compositional and nanomechanical properties with fragility fracture history, disease, and pharmacologic treatment. Computational studies have demonstrated that models with heterogeneous material properties predict apparent stiffness moderately better than homogeneous models and show greater energy dissipation. Collectively, these results suggest that microscale material heterogeneity affects not only microscale mechanics but also structural performance at larger length scales.
PMID:25383615
Diaz awarded ELI Undergraduate Research Award
David Diaz was awarded an Engineering Learning Initiatives Undergraduate Research Award for his proposal entitled, “Assessment of bone tissue composition in a mouse model of Type II diabetes.” The ELI grant provides support for research expenses for his research in the lab this fall. Congratulations David!
Lloyd receives 2014 ASBMR Young Investigator Award
The American Society for Bone and Mineral Research has awarded PhD student Ashley Lloyd a 2014 Young Investigator Award for her abstract “Cortical Tissue from Postmenopausal Women with Atypical Fractures Shows Reduced Heterogeneity in Nanomechanical Properties.” She will accept the award at the ASBMR Annual Meeting in Houston, TX September 11-15 2014.
Lloyd selected to participate in EFF/ASBMR Eighth Fellows Forum on Metabolic Bone Diseases
PhD student Ashley Lloyd was selected to participate in the Endocrine Fellows Foundation/American Society for Bone and Mineral Research (ASBMR) Eighth Fellows Forum on Metabolic Bone Diseases. She will attend the forum prior to the 2014 ASBMR annual meeting at the at the Hilton Americas Houston, Houston, TX, September 10-11, 2014.
Congratulations to MSE Class of 2014!
On Sunday, May 25 we celebrated Cornell’s 2014 Commencement. Congratulations to to the MSE Class of 2014 and especially to Donnelly Lab graduating seniors Michelle Chin and Vinny Wang!
Diaz wins ELI Undergraduate Research Award
David Diaz was awarded an Engineering Learning Initiatives Undergraduate Research Award for his proposal entitled, “Assessment of bone tissue composition in a mouse model of Type II diabetes.” The ELI grant provides support for research expenses for his research in the lab this summer. Congratulations David!
Donnelly E, Lane JM, and Boskey AL. Research perspectives: The 2013 AAOS/ORS research symposium on Bone Quality and Fracture Prevention. J Orthop Res. 2014.
Abstract
Bone fracture resistance is determined by the amount of bone present (“bone quantity”) and by a number of other geometric and material factors grouped under the term “bone quality.” In May 2013, a workshop was convened among a group of clinicians and basic science investigators to review the current state of the art in Bone Quality and Fracture Prevention and to make recommendations for future directions for research. The AAOS/ORS/OREF workshop was attended by 64 participants, including two representatives of the National Institutes of Arthritis and Musculoskeletal and Skin Diseases and 13 new investigators whose posters stimulated additional interest. A key outcome of the workshop was a set of recommendations regarding clinically relevant aspects of both bone quality and quantity that clinicians can use to inform decisions about patient care and management. The common theme of these recommendations was the need for more education of clinicians in areas of bone quality and for basic science studies to address specific topics of pathophysiology, diagnosis, prevention, and treatment of altered bone quality. In this report, the organizers with the assistance of the speakers and other attendees highlight the major findings of the meeting that justify the recommendations and needs for this field.
- PMID: 24700449
Halarnkar wins ELI Undergraduate Research Award
Natasha Halarnkar was awarded an Engineering Learning Initiatives Undergraduate Research Award for her proposal entitled, “Assessment of bone tissue composition in a mouse model of Type II diabetes.” The ELI grant provides support for research expenses for her research in the lab this summer. Congratulations Natasha!
Donnelly presents at Johns Hopkins University Endocrine Grand Rounds
Prof. Donnelly presented a talk entitled, “Reduced bone tissue compositional heterogeneity with bisphosphonate treatment in postmenopausal women with typical and atypical fragility fractures” at Endocrine Grand Rounds at Johns Hopkins University Medical School in Baltimore, MD.
Donnelly Research Lab 
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